What is Polyglutamic Acid?
Polyglutamic acid (PGA), also known as γ-polyglutamic acid, is a water-soluble peptide polymer produced through fermentation, most commonly by Bacillus subtilis. Unlike standard peptides, PGA is built from glutamic acid units linked by γ-amide bonds, giving it exceptional moisture-binding ability. It appears as a fine white to off-white powder with high water solubility and is listed under INCI as Polyglutamic Acid. CAS 25513-46-6 is commonly referenced for cosmetic and nutraceutical grades.
How Does It Work?
PGA forms a silky, breathable film on the skin that locks in hydration and reduces transepidermal water loss. Studies suggest it can hold up to four times more moisture than hyaluronic acid, making it a standout humectant for long-lasting plumping and smoothness. Beyond surface hydration, PGA supports the skin barrier and can enhance the absorption of co-formulated actives, improving the overall performance of serums and creams.
Its biocompatible, non-irritating profile also makes it suitable for sensitive-skin formulations and daily-use products where a lightweight, non-sticky feel is essential.
Five Key Application Areas
- Hydrating serums and essences — delivers deep, lasting moisture without tackiness.
- Anti-aging creams and lotions — plumps fine lines and improves skin smoothness.
- Moisturizing masks and mists — provides instant refreshment and barrier support.
- Sensitive-skin and barrier-repair lines — gentle, soothing hydration for reactive skin.
- Nutraceutical and oral beauty supplements — supports skin hydration from within.
VeraVita Biotech Supply Advantage
At VeraVita Biotech, we supply high-purity polyglutamic acid powder suitable for cosmetic and nutraceutical applications. Our material is available as ≥99% PGA (HPLC), with COA, MSDS, and technical documents available upon request. We support custom sample sizing, OEM/ODM formulation partnerships, and reliable bulk supply for brands worldwide.
For specifications, pricing, or samples, contact us at info@veravitabio.com.